NEFH anticorps
Aperçu rapide pour NEFH anticorps (ABIN6297898)
Antigène
Voir toutes NEFH AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Fonction
- Mouse anti-Human/Mouse/Rat/Chicken/Pig Neurofilament Antibody Cocktail [Sodium Azide Free]
-
Specificité
- Cytoplasmic
-
Purification
- Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
-
Immunogène
- Triton-X 100 insoluble proteins of rat brain (RT-97) and Neurofilaments from porcine spinal cord (NR-4) were used as the immunogen for the Neurofilament antibody cocktail.
-
-
-
-
Indications d'application
-
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
Restrictions
- For Research Use only
-
-
-
Buffer
- In 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
-
-
- NEFH (Neurofilament, Heavy Polypeptide (NEFH))
-
Autre désignation
- Neurofilament heavy polypeptide
-
Sujet
-
Target Description: This mAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.
Gene Symbol: NEFH///KIAA0845///NFH
-
ID gène
- 4744
-
UniProt
- P12036
Antigène
-