Erythrocyte Ankyrin anticorps (C-Term)

N° du produit ABIN630429

Cet anticorps anti-Erythrocyte Ankyrin est un anticorps Lapin Polyclonal détectant Erythrocyte Ankyrin dans WB et IHC. Adapté pour Humain, Souris, Rat et Chien.

Aperçu rapide pour Erythrocyte Ankyrin anticorps (C-Term) (ABIN630429)

Antigène: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Erythrocyte Ankyrin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Erythrocyte Ankyrin anticorps

Épitope: C-Term

Specificité: Ankyrin 1 antibody was raised against the C terminal of ANK1

Purification: Purified

Immunogène: Ankyrin 1 antibody was raised using the C terminal of ANK1 corresponding to a region with amino acids VVRQIDLSSADAAQEHEEVELRGSGLQPDLIEGRKGAQIVKRASLKRGKQ

Information d'application

Indications d'application: WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Ankyrin 1 Blocking Peptide, (ABIN5612074), is also available for use as a blocking control in assays to test for specificity of this Ankyrin 1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ANK1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur Erythrocyte Ankyrin

Antigène: Erythrocyte Ankyrin (ANK1) (Ankyrin 1, Erythrocytic (ANK1))

Autre désignation: Ankyrin 1

Sujet: Ankyrins are a family of proteins that are believed to link the integral membrane proteins to the underlying spectrin-actin cytoskeleton and play key roles in activities such as cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin 1, the prototype of this family, was first discovered in the erythrocytes, but since has also been found in brain and muscles. Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis. Complex patterns of alternative splicing in the regulatory domain, giving rise to different isoforms of ankyrin 1 have been described, however, the precise functions of the various isoforms are not known.

Poids moléculaire: 17 kDa (MW of target protein)

Pathways: Synaptic Membrane