Gephyrin anticorps (N-Term)

N° du produit ABIN630781

Cet anticorps Lapin Polyclonal détecte spécifiquement Gephyrin dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Gephyrin anticorps (N-Term) (ABIN630781)

Antigène: Gephyrin (GPHN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Gephyrin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Gephyrin anticorps

Épitope: N-Term

Specificité: Gephyrin antibody was raised against the N terminal of GPHN

Purification: Affinity purified

Immunogène: Gephyrin antibody was raised using the N terminal of GPHN corresponding to a region with amino acids HDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTED

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Gephyrin Blocking Peptide, (ABIN939094), is also available for use as a blocking control in assays to test for specificity of this Gephyrin antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GPHN antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur Gephyrin

Antigène: Gephyrin (GPHN)

Autre désignation: Gephyrin

Sujet: GPHN is a neuronal assembly protein that anchors inhibitory neurotransmitter receptors to the postsynaptic cytoskeleton via high affinity binding to a receptor subunit domain and tubulin dimers. In nonneuronal tissues, the protein is also required for molybdenum cofactor biosynthesis. Mutations in this gene may be associated with the neurological condition hyperplexia and also lead to molybdenum cofactor deficiency. Numerous alternatively spliced transcript variants encoding different isoforms have been described, however, the full-length nature of all transcript variants is not currently known.

Poids moléculaire: 80 kDa (MW of target protein)

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development