HAAO anticorps (N-Term)

N° du produit ABIN631165

Détail du produit anti-HAAO anticorps

Antigène: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAAO est non-conjugé

Application: Western Blotting (WB)

Specificité: HAAO antibody was raised against the N terminal of HAAO

Purification: Affinity purified

Immunogène: HAAO antibody was raised using the N terminal of HAAO corresponding to a region with amino acids HRDVVIRQGEIFLLPARVPHSPQRFANTVGLVVERRRLETELDGLRYYVG

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

HAAO Blocking Peptide, catalog no. 33R-3836, is also available for use as a blocking control in assays to test for specificity of this HAAO antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of HAAO antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur HAAO

Antigène: HAAO (3-hydroxyanthranilate 3,4-Dioxygenase (HAAO))

Autre désignation: HAAO (HAAO Produits)

Synonymes: anticorps Afu2g17450, anticorps 0610007K21Rik, anticorps 0610012J07Rik, anticorps 3-HAO, anticorps 3-HAOxase, anticorps 3HAO, anticorps zgc:103585, anticorps HAO, anticorps 3-hydroxyanthranilate 3,4-dioxygenase, anticorps 3-hydroxyanthranilate 3,4-dioxygenase L homeolog, anticorps SPO1774, anticorps CNB05620, anticorps AFUA_2G17450, anticorps Bcep18194_C7641, anticorps Kfla_5491, anticorps Micau_4935, anticorps RBRH_03005, anticorps Krodi_1278, anticorps haao, anticorps HAAO, anticorps Haao, anticorps haao.L

Sujet: 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders.

Poids moléculaire: 32 kDa (MW of target protein)