SH3RF1 anticorps (Middle Region)

N° du produit ABIN631195

Détail du produit anti-SH3RF1 anticorps

Antigène: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3RF1 est non-conjugé

Application: Western Blotting (WB)

Specificité: SH3 RF1 antibody was raised against the middle region of SH3 F1

Purification: Affinity purified

Immunogène: SH3 RF1 antibody was raised using the middle region of SH3 F1 corresponding to a region with amino acids LLKLLSGASTKRKPRVSPPASPTLEVELGSAELPLQGAVGPELPPGGGHG

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

SH3RF1 Blocking Peptide, catalog no. 33R-5155, is also available for use as a blocking control in assays to test for specificity of this SH3RF1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SH0 F1 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur SH3RF1

Antigène: SH3RF1 (SH3 Domain Containing Ring Finger 1 (SH3RF1))

Autre désignation: SH3RF1 (SH3RF1 Produits)

Synonymes: anticorps SH3MD2, anticorps posh, anticorps xPOSH, anticorps rnf142, anticorps sh3md2, anticorps MGC135632, anticorps MGC189605, anticorps POSH, anticorps RNF142, anticorps 2200003J05Rik, anticorps Posh, anticorps R75531, anticorps Sh3md2, anticorps si:ch211-114c9.2, anticorps si:dkey-15j16.4, anticorps wu:fi42f11, anticorps SH3 domain containing ring finger 1, anticorps SH3 domain containing ring finger 1 S homeolog, anticorps SH3RF1, anticorps sh3rf1, anticorps sh3rf1.S, anticorps Sh3rf1

Sujet: SH3RF1 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3RF1 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane.

Poids moléculaire: 93 kDa (MW of target protein)