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NECAB3 anticorps (N-Term)

Cet anticorps anti-NECAB3 est un anticorps Lapin Polyclonal détectant NECAB3 dans WB. Adapté pour Humain.
N° du produit ABIN632067

Aperçu rapide pour NECAB3 anticorps (N-Term) (ABIN632067)

Antigène

Voir toutes NECAB3 Anticorps
NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

Reactivité

  • 23
  • 18
  • 7
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 22
  • 1
Lapin

Clonalité

  • 23
Polyclonal

Conjugué

  • 16
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp NECAB3 est non-conjugé

Application

  • 16
  • 9
  • 7
  • 6
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Épitope

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Specificité

    NECAB3 antibody was raised against the N terminal of NECAB3

    Purification

    Affinity purified

    Immunogène

    NECAB3 antibody was raised using the N terminal of NECAB3 corresponding to a region with amino acids MACAGLLTVCLLRPPAPQPQPQTPRHPQLAPDPGPAGHTLFQDVFRRADK
  • Indications d'application

    WB: 1 µg/mL
    Optimal conditions should be determined by the investigator.

    Commentaires

    NECAB3 Blocking Peptide, (ABIN5614947), is also available for use as a blocking control in assays to test for specificity of this NECAB3 antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of NECAB3 antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène

    NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3 (NECAB3))

    Autre désignation

    NECAB3

    Sujet

    The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

    Poids moléculaire

    44 kDa (MW of target protein)
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