MCM10 anticorps (Middle Region)

N° du produit ABIN634085

Détail du produit anti-MCM10 anticorps

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MCM10 est non-conjugé

Application: Western Blotting (WB)

Specificité: MCM10 antibody was raised against the middle region of MCM10

Purification: Affinity purified

Immunogène: MCM10 antibody was raised using the middle region of MCM10 corresponding to a region with amino acids PKLSALAEAKKLAAITKLRAKGQVLTKTNPNSIKKKQKDPQDILEVKERV

Information d'application

Indications d'application: WB: 1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MCM10 Blocking Peptide, catalog no. 33R-7173, is also available for use as a blocking control in assays to test for specificity of this MCM10 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Lyophilized powder. Add distilled water for a 1 mg/mL concentration of MCM10 antibody in PBS

Concentration: Lot specific

Buffer: PBS

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.

Détails sur MCM10

Antigène: MCM10 (Minichromosome Maintenance Deficient 10 (MCM10))

Autre désignation: MCM10 (MCM10 Produits)

Synonymes: anticorps CG9241, anticorps DmMCM10, anticorps Dmel\\CG9241, anticorps Scim19, anticorps mcm10, anticorps CNA43, anticorps DNA43, anticorps xmcm10, anticorps 2410041F14Rik, anticorps AU018508, anticorps C330019M07Rik, anticorps C79164, anticorps Minichromosome maintenance 10, anticorps minichromosome maintenance 10 replication initiation factor, anticorps minichromosome maintenance 10 replication initiation factor L homeolog, anticorps Mcm10, anticorps MCM10, anticorps mcm10.L

Sujet: This protein is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding.

Poids moléculaire: 98 kDa (MW of target protein)

Pathways: Mitotic G1-G1/S Phases, DNA Replication