Doublecortin anticorps
Aperçu rapide pour Doublecortin anticorps (ABIN634473)
Antigène
Voir toutes Doublecortin (DCX) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Affinity purified
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Immunogène
- DCX antibody was raised using a synthetic peptide corresponding to a region with amino acids TAGPKASPTPQKTSAKSPGPMRRSKSPADSANGTSSSQLSTPKSKQSPIS
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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DCX Blocking Peptide, (ABIN5613146), is also available for use as a blocking control in assays to test for specificity of this DCX antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of DCX antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- Doublecortin (DCX)
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Autre désignation
- DCX
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Sujet
- In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. DCX is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The protein contains two doublecortin domains, which bind microtubules. In addition, DCX interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex.
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Poids moléculaire
- 49 kDa (MW of target protein)
Antigène
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