SIGLEC10 anticorps (Middle Region)
Aperçu rapide pour SIGLEC10 anticorps (Middle Region) (ABIN634727)
Antigène
Voir toutes SIGLEC10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Specificité
- SIGLEC10 antibody was raised against the middle region of SIGLEC10
-
Purification
- Affinity purified
-
Immunogène
- SIGLEC10 antibody was raised using the middle region of SIGLEC10 corresponding to a region with amino acids CHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYL
-
-
-
-
Indications d'application
-
WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
-
SIGLEC10 Blocking Peptide, (ABIN937100), is also available for use as a blocking control in assays to test for specificity of this SIGLEC10 antibody
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of SIGLEC10 antibody in PBS
-
Concentration
- Lot specific
-
Buffer
- PBS
-
Conseil sur la manipulation
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
-
-
- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
-
Autre désignation
- SIGLEC10
-
Sujet
- SIGLEC10 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. SIGLEC10 preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, SIGLEC10 may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules.
-
Poids moléculaire
- 76 kDa (MW of target protein)
Antigène
-