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Glyco anticorps

L’anticorps Lapin Polyclonal anti- a été validé pour WB. Il convient pour détecter dans des échantillons de Humain.
N° du produit ABIN634766

Aperçu rapide pour Glyco anticorps (ABIN634766)

Antigène

Glyco

Reactivité

Humain

Hôte

Lapin

Clonalité

Polyclonal

Application

Western Blotting (WB)
  • Purification

    Affinity purified

    Immunogène

    Glycoprotein Ib antibody was raised using a synthetic peptide corresponding to a region with amino acids RGSLPTFRSSLFLWVRPNGRVGPLVAGRRPSALSQGRGQDLLSTVSIRYS
  • Indications d'application

    WB: 0.25 µg/mL
    Optimal conditions should be determined by the investigator.

    Commentaires

    Glycoprotein Ib Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this Glycoprotein Ib antibody

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Lyophilized powder. Add distilled water for a 1 mg/mL concentration of GP0 A antibody in PBS

    Concentration

    Lot specific

    Buffer

    PBS

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
  • Antigène

    Glyco

    Classe de substances

    Viral Protein

    Sujet

    Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that are linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. GP1BA is the alpha subunit.

    Poids moléculaire

    68 kDa (MW of target protein)
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