TMEM123 anticorps (C-Term)
Aperçu rapide pour TMEM123 anticorps (C-Term) (ABIN635901)
Antigène
Voir toutes TMEM123 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- TMEM123 antibody was raised against the C terminal of TMEM123
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Purification
- Affinity purified
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Immunogène
- TMEM123 antibody was raised using the C terminal of TMEM123 corresponding to a region with amino acids SSVTITTTMHSEAKKGSKFDTGSFVGGIVLTLGVLSILYIGCKMYYSRRG
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Indications d'application
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WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Commentaires
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TMEM123 Blocking Peptide, (ABIN5616659), is also available for use as a blocking control in assays to test for specificity of this TMEM123 antibody
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of TMEM123 antibody in PBS
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Concentration
- Lot specific
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Buffer
- PBS
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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Autre désignation
- TMEM123
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Sujet
- TMEM123 is a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti-PORIMIN (pro-oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. TMEM123 is proposed to function as a cell surface receptor that mediates cell death.
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Poids moléculaire
- 19 kDa (MW of target protein)
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Pathways
- Regulation of Cell Size
Antigène
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