AMACR anticorps (AA 33-48)
Aperçu rapide pour AMACR anticorps (AA 33-48) (ABIN636371)
Antigène
Voir toutes AMACR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 33-48
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Purification
- Affinity chromatography purified
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Immunogène
- AMACR antibody was raised in rabbit using AA 33-48 [RVDRPGSRYDVSRLGR] of the 42 kDa human AMACR (P504 S) protein as the immunogen.
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Isotype
- IgG
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Indications d'application
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IHC: 1:100, WB: 1:500. For IHC, an incubation period of 30 minutes at room temperature is suggested. Formalin fixed paraffin embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Concentration
- Lot specific
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Buffer
- Affinity purified and supplied in PBS, with 0.02 % NaN3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Autre désignation
- AMACR
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Sujet
- Alpha-methylacyl-CoA racemase (AMACR), (also known as P504S) is an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids. Recent studies have shown that, compared with expression in normal or benign prostate epithelium, AMACR is consistently overexpressed in prostate cancer epithelium, making it a specific marker for cancer cells within the prostate gland.
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Pathways
- Monocarboxylic Acid Catabolic Process
Antigène
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