TNFSF14 anticorps

N° du produit ABIN636620

Détail du produit anti-TNFSF14 anticorps

Antigène: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNFSF14 est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Purification: Purified

Immunogène: LIGHT antibody was raised in rabbit using highly pure recombinant human LIGHT as the immunogen.

Information d'application

Indications d'application: Optimal conditions should be determined byt he investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur TNFSF14

Antigène: TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))

Abstract: TNFSF14 Produits

Synonymes: anticorps TNFSF14, anticorps CD258, anticorps HVEML, anticorps LIGHT, anticorps LTg, anticorps TR2, anticorps HVEM-L, anticorps Ly113, anticorps TNF superfamily member 14, anticorps tumor necrosis factor (ligand) superfamily, member 14, anticorps TNFSF14, anticorps Tnfsf14

Sujet: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

Poids moléculaire: 20.1 kDa (predicted detection band MW)

Pathways: Cancer Immune Checkpoints