L’anticorps Lapin Polyclonal anti-RELM alpha a été validé pour WB, ELISA et Inhibition. Il convient pour détecter RELM alpha dans des échantillons de Souris. Il y a 1 publication disponible.
Reactivité: Souris, Rat
WB, IF (cc)
Hôte: Lapin
Polyclonal
AbBy Fluor® 488
Indications d'application
Optimal conditions should be determined byt he investigator.
Restrictions
For Research Use only
Format
Lyophilized
Concentration
Lot specific
Buffer
Lyophilized from PBS, pH 7.2.
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles. Dilute only prior to immediate use.
Stock
4 °C/-20 °C
Stockage commentaire
Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
Wang, Ismahil, Zhu, Rokosh, Hamid, Zhou, Pogwizd, Prabhu: "CD206+IL-4Rα+ Macrophages Are Drivers of Adverse Cardiac Remodeling in Ischemic Cardiomyopathy." dans: Circulation, Vol. 152, Issue 4, pp. 257-273, (2025) (PubMed).
Antigène
RELM alpha
Sujet
RELM-alpha belongs to a unique family of tissue-specific cytokines termed FIZZ (found in inflammatory zone) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta are 85-94 amino acid secreted proteins sharing a conserved C-terminal domain characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. RELM-alpha and Resistin are secreted exclusively by adipocytes while RELM-beta is expressed in the epithelium of the colon and small bowel. The physiological role and molecular targets of RELM-alpha re still unknown.