IL-31 anticorps
Aperçu rapide pour IL-31 anticorps (ABIN636667)
Antigène
Voir toutes IL-31 (IL31) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Purified
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Immunogène
- IL31 antibody was raised in rabbit using highly pure recombinant human IL-31 as the immunogen.
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Indications d'application
- Optimal conditions should be determined byt he investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS, pH 7.2.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- IL-31 (IL31) (Interleukin 31 (IL31))
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Autre désignation
- IL31
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Sujet
- IL31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases.
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Poids moléculaire
- 15.8 kDa (predicted detection band MW)
Antigène
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