Dinitrophenol anticorps

N° du produit ABIN636762

Détail du produit anti-Dinitrophenol anticorps

Antigène: Dinitrophenol (DNP)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Dinitrophenol est non-conjugé

Application: ELISA, Western Blotting (WB)

Immunogène: Dinitrophenol antibody was raised in goat using dinitrophenol-modified protein as the immunogen.

Information d'application

Indications d'application: ELISA: >1:4,000, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Références pour anticorps anti-Dinitrophenol (ABIN636762)

Fan, Schrott, Snelling, Felty, Graham, McGauly, Arnold, Korneeva: "Carbonyl-protein content increases in brain and blood of female rats after chronic oxycodone treatment." dans: BMC neuroscience, Vol. 21, Issue 1, pp. 4, (2020) (PubMed).

Détails sur Dinitrophenol

Antigène: Dinitrophenol (DNP)

Autre désignation: DNP (DNP Produits)

Classe de substances: Chemical

Sujet: Tissues are continually exposed to reactive oxygen species (ROS) that are produced in tissues from metabolism processes or the inflammatory response of leukocytes or macrophages. It is estimated that as much as 1 % of consumed oxygen may be converted to ROS, which can cause damage to various cellular components. Proteins are one of the cellular components most vulnerable to oxidative damage by ROS, which results in an increase in protein carbonyl content. This oxidative modification of proteins can lead to cross-linking, peptide fragmentation, modified residues and the conversion of one amino group to another. If sufficient protein damage accumulates, cell death will occur.