GRM2 anticorps

N° du produit ABIN636930

Détail du produit anti-GRM2 anticorps

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogène: GRM2 antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Information d'application

Indications d'application: IHC-P: 4 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Détails sur GRM2

Antigène: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Autre désignation: GRM2 (GRM2 Produits)

Synonymes: anticorps GLUR2, anticorps GPRC1B, anticorps MGLUR2, anticorps mGlu2, anticorps 4930441L02Rik, anticorps Gprc1b, anticorps mGluR2, anticorps mGluR7, anticorps glutamate metabotropic receptor 2, anticorps glutamate receptor, metabotropic 2, anticorps GRM2, anticorps Grm2

Sujet: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. The receptors in group II, including mGluRs 2 and 3, and group III, including mGluRs 4, 6, 7, and 8, (with some exceptions) prevent the formation of cyclic adenosine monophosphate, or cAMP, by activating a G protein that inhibits the enzyme adenylyl cyclase, which forms cAMP from ATP.

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport