PDE8B anticorps

N° du produit ABIN636941

L’anticorps anti-PDE8B Polyclonal Lapin est utilisé pour la détection de PDE8B dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour PDE8B anticorps (ABIN636941)

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PDE8B anticorps

Purification: Affinity chromatography purified

Immunogène: PDE8 B antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Information d'application

Indications d'application: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B

Sujet: Phosphodiesterases (PDEs) are a family of related phosphohydrolyases that selectively catalyze the hydrolysis of 3' cyclic phosphate bonds in adenosine and/or guanine 3',5' cyclic monophosphate (cAMP and/or cGMP). They regulate the cellular levels, localization and duration of action of these second messengers by controlling the rate of their degradation. PDE1-11, PDE4, 7 and 8 selectively degrade cAMP. These enzymes are involved in many signal transduction pathways.

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process