Prostaglandin E Synthase anticorps

N° du produit ABIN636994

Détail du produit anti-Prostaglandin E Synthase anticorps

Antigène: Prostaglandin E Synthase (PTGES)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Prostaglandin E Synthase est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Affinity chromatography purified

Immunogène: PTGES antibody was raised in rabbit using a synthetic peptide conjugated to KLH as the immunogen.

Information d'application

Indications d'application: IHC-P: 10 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: Purified by Immunoaffinity Chromatography and supplied in PBS with 0.1 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -70 °C for long term storage.

Détails sur Prostaglandin E Synthase

Antigène: Prostaglandin E Synthase (PTGES)

Autre désignation: PTGES (PTGES Produits)

Synonymes: anticorps ptges, anticorps MGC80290, anticorps PTGES, anticorps MGST-IV, anticorps MGST1-L1, anticorps MGST1L1, anticorps MPGES, anticorps PGES, anticorps PIG12, anticorps PP102, anticorps PP1294, anticorps TP53I12, anticorps mPGES-1, anticorps 2410099E23Rik, anticorps D2Ertd369e, anticorps Pges, anticorps mPGES, anticorps MPGES-1, anticorps prostaglandin E synthase, anticorps prostaglandin E synthase S homeolog, anticorps PTGES, anticorps ptges.S, anticorps Ptges

Sujet: Prostaglandin E synthase is an enzyme that in humans is encoded by the PTGES gene. The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53-induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.