HPV16 E7 anticorps
Aperçu rapide pour HPV16 E7 anticorps (ABIN639902)
Antigène
Voir toutes HPV16 E7 (HPV-16 E7) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Mouse Anti-HPV 16 Oncoprotein E7
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Specificité
- DS-MB-03401 recognizes both the monomer and dimer forms of the E7 oncoprotein of human papilloma virus 16. Human papillomavirus (HPV) is a diverse group of DNA-based viruses that infect skin and mucous membranes of humans and animals. Some HPV types are the causative agents of cervical cancer, with types 16 and 18 being particularly high-risk. The viral proteins E6 and E7 disrupts normal cell cycle regulation by interacting with p53 (a tumor-suppressing transcription factor) and Rb (retinoblastoma protein, also a tumor-suppressor). E7 particularly binds to Rb and histone deacetylases, resulting in activation of the E2F genes, which code for a family of transcription factors. The viral proteins E6 and E7 might be of particular interest in the development of therapeutic vaccines, since they are expressed early in viral infection. DS-MB-03401 cross-reacts with both the monomer and dimer forms of the E7 protein of HPV-18.
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Attributs du produit
- Bacterial/Fungal/Parasitic/Viral Antigens
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Purification
- Purified
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Immunogène
- Oncoprotein E7 from human papillomavirus 16.
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Isotype
- IgG2a
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Indications d'application
- ELISA, Western Blotting
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- HPV16 E7 (HPV-16 E7) (Human Papilloma Virus 16 E7 (HPV-16 E7))
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Classe de substances
- Viral Protein
Antigène
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