PD-1 anticorps

N° du produit ABIN642272

L’anticorps Rat anti-PD-1 a été validé pour FACS. Il convient pour détecter PD-1 dans des échantillons de Souris.

Aperçu rapide pour PD-1 anticorps (ABIN642272)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Souris

Hôte: Rat

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Flow Cytometry (FACS)

Détail du produit anti-PD-1 anticorps

Specificité: DS-MB-03795 recognizes mouse CD279, a 55kD cell surface protein which is a member of the CD28/CTLA-4 family, otherwise known as Programmed Death-1 (PD-1). CD279 is expressed predominantly on activated T- and B- lymphocytes and on a subset of thymocytes. Studies suggest that CD279, an immunoinhibitory receptor, plays a critical role in peripheral tolerance induction and prevention of autoimmune disease. Two members of the B7 family, B7-H1 (PD-L1) and B7-DC (PD-L2), have been identified as the ligands for CD279. DS-MB-03795 does not block the binding of both B7-H1-Ig and B7-DC-Ig fusion proteins to PD-1 transfected BHK cells.

Attributs du produit: Rat Anti-Mouse CD279

Purification: Purified

Immunogène: PD-1 transferred BHK cells

Isotype: IgG2b

Information d'application

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline, pH7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279

Sujet: Synonyms: PD1

Pathways: Cancer Immune Checkpoints