MUC1 anticorps

N° du produit ABIN643712

L’anticorps anti-MUC1 Monoclonal Souris est utilisé pour la détection de MUC1 dans des échantillons de Humain. Il a été validé pour FACS, IHC (p), IP et IHC (fro).

Aperçu rapide pour MUC1 anticorps (ABIN643712)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-MUC1 anticorps

Fonction: Mouse Anti-Human Mucin 1

Specificité: Mucins are a family of high molecular weight, heavily glycosylated proteins (glycoconjugates) produced by many epithelial tissues in vertebrates. DS-MB-01935 recognizes CD227, also known as mucin 1 which is a breast cancer associated mucin encoded by the Muc-1 gene. CD227 is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. This protein is overexpressed abundantly in >90% breast carcinomas and metastases. The dominant epitope recognized by this antibody is the 12-mer GVTSAPDTRPAP of the mucin 1 tandem repeat. DS-MB-01935 has been tested on frozen human ovarian carcinoma tissue sections and paraffin embedded sections from normal breast tissue. This antibody also reacts weakly with sections of small intestine and colon.

Purification: Purified

Immunogène: Human breast cancer cell line ZR-75-1.

Isotype: IgG1

Information d'application

Indications d'application: Immunohistology - Frozen, Flow Cytometry, Immunoprecipitation, Immunohistology - Paraffin

Restrictions: For Research Use only

Stockage

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: -20°C

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: CD227

Pathways: Negative Regulation of intrinsic apoptotic Signaling