EBV LMP2A anticorps
Cet anticorps anti-EBV LMP2A est un anticorps Rat détectant EBV LMP2A dans IHC (p) et WB. Adapté pour Epstein-Barr Virus (EBV).
N° du produit ABIN644979
Aperçu rapide pour EBV LMP2A anticorps (ABIN644979)
Antigène
EBV LMP2A
(Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
Reactivité
Epstein-Barr Virus (EBV)
Hôte
Rat
Conjugué
Cet anticorp EBV LMP2A est non-conjugé
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
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Specificité
- DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
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Attributs du produit
- Rat Anti-Epstein-Barr Virus LMP2A
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Purification
- Purified
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Immunogène
- Bacterial TrpE-LMP2A fusion protein
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Isotype
- IgG2a
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Restrictions
- For Research Use only
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Concentration
- IgG concentration 1.0 mg/ml
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Buffer
- Phosphate buffered saline
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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- EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
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Autre désignation
- Epstein-Barr Virus LMP2A
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Classe de substances
- Viral Protein
Antigène
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