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EBV LMP2A anticorps

EBV LMP2A Reactivité: Epstein-Barr Virus (EBV) IHC (p), WB Hôte: Rat unconjugated
N° du produit ABIN644979
  • Antigène Tous les produits EBV LMP2A
    EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
    Reactivité
    Epstein-Barr Virus (EBV)
    Hôte
    • 1
    Rat
    Conjugué
    • 1
    Cet anticorp EBV LMP2A est non-conjugé
    Application
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Specificité
    DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.
    Attributs du produit
    Rat Anti-Epstein-Barr Virus LMP2A
    Purification
    Purified
    Immunogène
    Bacterial TrpE-LMP2A fusion protein
    Isotype
    IgG2a
  • Restrictions
    For Research Use only
  • Concentration
    IgG concentration 1.0 mg/ml
    Buffer
    Phosphate buffered saline
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))
    Autre désignation
    Epstein-Barr Virus LMP2A (EBV LMP2A Produits)
    Synonymes
    anticorps -, anticorps LMP2A
    Classe de substances
    Viral Protein
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