Retinoid X Receptor alpha anticorps

N° du produit ABIN645871

Cet anticorps Chèvre not_set détecte spécifiquement Retinoid X Receptor alpha. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Retinoid X Receptor alpha anticorps (ABIN645871)

Antigène: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Reactivité: Humain, Souris, Rat

Hôte: Chèvre

Conjugué: Cet anticorp Retinoid X Receptor alpha est non-conjugé

Application: Veuillez nous consulter SVP

Détail du produit anti-Retinoid X Receptor alpha anticorps

Specificité: The Goat anti-RXR alpha antibody detects protein derived from human recombinant protein and A431 cell lysate at various concentrations.

Réactivité croisée: Humain, Souris, Rat (Rattus)

Attributs du produit: Goat Anti-RXR alpha

Immunogène: Peptide with sequence CQVNSSLTSPTGRGSM, from the internal region of the protein sequence according to NP_002948, was used as an immunogen.

Isotype: IgG

Information d'application

Restrictions: For Research Use only

Stockage

Reconstitution: Supplied as 100µg of purified antibody. 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Please avoid freeze-thaw cycles.

Stock: -20 °C

Détails sur Retinoid X Receptor alpha

Antigène: Retinoid X Receptor alpha (RXRA) (Retinoid X Receptor, alpha (RXRA))

Autre désignation: RXR alpha

Sujet: Retinoid X receptors (RXRs) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptor proteins that exert their effects by binding to specific DNA response elements, thus regulating gene expression in target cells. The RXR subfamily consists of at least three similar genes, RXR alpha, RXR beta and RXR gamma, all of which control transcription of target genes mediated by retinoids. RXR beta controls expression of many genes that respond to hormones and vitamins, including thyroid hormone, estrogen, retinoids and vitamin D. RXR beta controls a wide array of genes because of its ability to heterodimerize with other hormone receptors including the thyroid hormone receptor (THR), vitamin D receptor (VDR) and retinoic acid receptor (RAR).

NCBI Accession: NP_002948

Pathways: Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Hepatitis C