CRISP3
Reactivité: Souris
WB, IF (cc), IF (p)
Hôte: Lapin
Polyclonal
AbBy Fluor® 594
Indications d'application
Flow cytometry: 1.2 µg/10^6 cells CELISA: 1:200 - 1:400 For each application a titration should be performed to determine the optimal concentration.
Restrictions
For Research Use only
Concentration
2 mg/mL
Buffer
PBS, pH 7.2
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C
Stockage commentaire
short term: 2 °C - 8 °C, long term: -20 °C
Antigène
CRISP3
(Cysteine-Rich Secretory Protein 3 (CRISP3))
Autre désignation
Crisp3
Sujet
Cysteine-rich secretory protein 3 (CRISP3) belongs to the cysteine-rich secretory protein family. CRISPs are characterized by a cysteine-rich domain at the COOH terminal that form 8 intramolecular disulfide bonds. Mammalian members of the CRISP family are expressed predominantly in the male reproductive tract and are implicated in the process of reproduction from spermiogenesis, posttesticular sperm maturation and capacitation to oocyte-sperm fusion. CRISP3 is epithelium-specific and found predominantly in salivary gland, pancreas and prostate, and in less abundance in the epididymis, ovary, thymus and colon. CRISP3 is up-regulated in malignant prostatic epithelium, therefore, it can be used as a potential prostate cancer biomarker.