IPO7 anticorps (N-Term)

N° du produit ABIN651626

L’anticorps Lapin Polyclonal anti-IPO7 a été validé pour WB et IHC (p). Il convient pour détecter IPO7 dans des échantillons de Humain et Souris.

Aperçu rapide pour IPO7 anticorps (N-Term) (ABIN651626)

Antigène: IPO7 (Importin 7 (IPO7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IPO7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB26876

Détail du produit anti-IPO7 anticorps

Épitope: AA 142-169, N-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IPO7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-169 amino acids from the N-terminal region of human IPO7.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur IPO7

Antigène: IPO7 (Importin 7 (IPO7))

Autre désignation: IPO7

Sujet: The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Poids moléculaire: 119517

ID gène: 10527

NCBI Accession: NP_006382

UniProt: O95373

Pathways: Protein targeting to Nucleus