Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

HAS2 anticorps (AA 138-166)

HAS2 Reactivité: Humain, Souris WB, FACS, IHC (p) Hôte: Lapin Polyclonal RB22492 unconjugated
N° du produit ABIN651874
  • Antigène Voir toutes HAS2 Anticorps
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Épitope
    • 9
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 138-166
    Reactivité
    • 41
    • 23
    • 14
    Humain, Souris
    Hôte
    • 37
    • 13
    Lapin
    Clonalité
    • 37
    • 13
    Polyclonal
    Conjugué
    • 15
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp HAS2 est non-conjugé
    Application
    • 30
    • 21
    • 13
    • 11
    • 7
    • 5
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This HAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-166 amino acids of human HAS2.
    Clone
    RB22492
    Isotype
    IgG
    Top Product
    Discover our top product HAS2 Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid freeze-thaw cycles.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
    Date de péremption
    6 months
  • Lien, Lee, Jeng, Lin, Lu, Yao: "Differential expression of hyaluronan synthase 2 in breast carcinoma and its biological significance." dans: Histopathology, Vol. 65, Issue 3, pp. 328-39, (2015) (PubMed).

    Kobayashi, Banno, Shimizu, Ueki, Tsuji, Masuda, Kisu, Nomura, Tominaga, Nagano, Saya, Aoki: "Gene expression profile of a newly established choriocarcinoma cell line, iC3-1, compared to existing choriocarcinoma cell lines and normal placenta." dans: Placenta, Vol. 34, Issue 2, pp. 110-8, (2013) (PubMed).

  • Antigène
    HAS2 (Hyaluronan Synthase 2 (HAS2))
    Autre désignation
    HAS2 (HAS2 Produits)
    Synonymes
    anticorps DG42, anticorps XHas2, anticorps Has2, anticorps hyaluronan synthase 2, anticorps hyaluronan synthase 2 S homeolog, anticorps has2, anticorps HAS2, anticorps Has2, anticorps SHAS2, anticorps has2.S
    Sujet
    Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1.
    Poids moléculaire
    63566
    ID gène
    3037
    NCBI Accession
    NP_005319
    UniProt
    Q92819
    Pathways
    Glycosaminoglycan Metabolic Process
Vous êtes ici:
Support technique