TUBB3 anticorps (AA 36-63)

N° du produit ABIN651938

Il existe 2+ publications pour ce produit. L’anticorps anti-TUBB3 Polyclonal Lapin est utilisé pour la détection de TUBB3 dans des échantillons de Humain et Souris. Il a été validé pour WB, FACS et IHC (p).

Aperçu rapide pour TUBB3 anticorps (AA 36-63) (ABIN651938)

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TUBB3 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB21098

Détail du produit anti-TUBB3 anticorps

Épitope: AA 36-63

Homologie: B, Pr, Rat, C

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TUBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids of human TUBB3.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-TUBB3 (ABIN651938)

Kazmierczak, Kazmierczak, Peng, Harris, Shah, Puel, Lenoir, Franco, Schwander: "Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 13, pp. 3447-3464, (2017) (PubMed).

Jeong, Martchenko, Cohen: "Calpain-dependent cytoskeletal rearrangement exploited for anthrax toxin endocytosis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 42, pp. E4007-15, (2013) (PubMed).

Détails sur TUBB3

Antigène: TUBB3 (Tubulin, beta 3 (TUBB3))

Autre désignation: TUBB3

Sujet: Beta III tubulin is abundant in the central and peripheral nervous systems (CNS and PNS) where it is prominently expressed during fetal and postnatal development. As exemplified in cerebellar and sympathoadrenal neurogenesis, the distribution of beta III is neuron-associated, exhibiting distinct temporospatial gradients according to the regional neuroepithelia of origin. However, transient expression of this protein is also present in the subventricular zones of the CNS comprising putative neuronal- and/or glial precursor cells, as well as in Kulchitsky neuroendocrine cells of the fetal respiratory epithelium. This temporally restricted, potentially non-neuronal expression may have implications in the identification of presumptive neurons derived from embryonic stem cells.

Poids moléculaire: 50433

ID gène: 10381

NCBI Accession: NP_001184110, NP_006077

UniProt: Q13509

Pathways: Dynamique des Microtubules, M Phase