FOXP2 anticorps (AA 657-684)

N° du produit ABIN651939

Cet anticorps anti-FOXP2 est un anticorps Lapin Polyclonal détectant FOXP2 dans WB et IF. Adapté pour Humain et Souris. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour FOXP2 anticorps (AA 657-684) (ABIN651939)

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXP2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: RB21207

Détail du produit anti-FOXP2 anticorps

Épitope: AA 657-684

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This FOXP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-684 amino acids of human FOXP2.

Isotype: IgG

Information d'application

Indications d'application: IF: 1:10~50. WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-FOXP2 (ABIN651939)

Vibulyaseck, Fujita, Luo, Tran, Oh-Nishi, Ono, Hirano, Sugihara: "Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum." dans: The Journal of comparative neurology, Vol. 525, Issue 14, pp. 2971-2990, (2018) (PubMed).

Fujita, Morita, Furuichi, Sugihara: "Clustered fine compartmentalization of the mouse embryonic cerebellar cortex and its rearrangement into the postnatal striped configuration." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 45, pp. 15688-703, (2012) (PubMed).

Détails sur FOXP2

Antigène: FOXP2 (Forkhead Box P2 (FOXP2))

Autre désignation: FOXP2

Sujet: FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.

Poids moléculaire: 79919

ID gène: 93986

NCBI Accession: NP_001166237, NP_001166238, NP_055306, NP_683696, NP_683697, NP_683698

UniProt: O15409