SIRT3 anticorps (C-Term)

N° du produit ABIN652184

Il existe 2+ publications pour ce produit. L’anticorps anti-SIRT3 Polyclonal Lapin est utilisé pour la détection de SIRT3 dans des échantillons de Humain et Souris. Il a été validé pour WB et IHC (p).

Aperçu rapide pour SIRT3 anticorps (C-Term) (ABIN652184)

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SIRT3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB25945

Détail du produit anti-SIRT3 anticorps

Épitope: AA 304-334, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This Sirt3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-334 amino acids from the C-terminal region of Mouse Sirt3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:64000. WB: 1:2000. WB: 1:2000. IHC-P: 1:50~100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.

Date de péremption: 6 months

Références pour anticorps anti-SIRT3 (ABIN652184)

Chen, Liu, Li, Wang, Liu, Li, Zhang, Bu: "Mouse SIRT3 attenuates hypertrophy-related lipid accumulation in the heart through the deacetylation of LCAD." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0118909, (2015) (PubMed).

Kawamura, Uchijima, Horike, Tonami, Nishiyama, Amano, Asano, Kurihara, Kurihara: "Sirt3 protects in vitro-fertilized mouse preimplantation embryos against oxidative stress-induced p53-mediated developmental arrest." dans: The Journal of clinical investigation, Vol. 120, Issue 8, pp. 2817-28, (2010) (PubMed).

Détails sur SIRT3

Antigène: SIRT3 (Sirtuin 3 (SIRT3))

Autre désignation: Sirt3

Sujet: SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The SIRT3 is included in class I of the sirtuin family.

Poids moléculaire: 36615

ID gène: 64384

NCBI Accession: NP_001120823, NP_001171275, NP_071878

UniProt: Q8R104