TTR anticorps (C-Term)
Aperçu rapide pour TTR anticorps (C-Term) (ABIN652227)
Antigène
Voir toutes TTR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 71-98, C-Term
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Homologie
- Pr
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This TTR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-98 amino acids from the C-terminal region of human TTR.
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Isotype
- Ig Fraction
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Indications d'application
- IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- TTR (Transthyretin (TTR))
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Autre désignation
- TTR
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Sujet
- Transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein, it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported, most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
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Poids moléculaire
- 15887
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ID gène
- 7276
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NCBI Accession
- NP_000362
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UniProt
- P02766
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Pathways
- Hormone Transport
Antigène
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