Protein Tob1 (TOB1) (AA 54-83), (N-Term) anticorps

N° du produit ABIN652511

Détail du produit

Antigène: Protein Tob1 (TOB1)

Épitope: AA 54-83, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Homologie: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This TOB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 54-83 amino acids from the N-terminal region of human TOB1.

Clone: RB19906

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: Protein Tob1 (TOB1)

Autre désignation: TOB1 (TOB1 Produits)

Synonymes: anticorps Tob, anticorps Trob, anticorps APRO5, anticorps APRO6, anticorps PIG49, anticorps TOB, anticorps TROB, anticorps TROB1, anticorps tob1, anticorps tob1l, anticorps wu:fb54d02, anticorps wu:fb98h12, anticorps wu:fd15f10, anticorps zgc:65837, anticorps transducer of ErbB-2.1, anticorps transducer of ERBB2, 1, anticorps transducer of ERBB2, 1a, anticorps transducer of ERBB2, 1 S homeolog, anticorps transducer of ERBB2, 1b, anticorps Tob1, anticorps TOB1, anticorps tob1a, anticorps tob1.S, anticorps tob1b

Sujet: TOB1 is a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

Poids moléculaire: 38155

ID gène: 10140

NCBI Accession: NP_001230806, NP_001230814, NP_005740

UniProt: P50616