E2F5 anticorps (N-Term)

N° du produit ABIN652951

Cet anticorps Lapin Polyclonal détecte spécifiquement E2F5 dans WB, FACS et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour E2F5 anticorps (N-Term) (ABIN652951)

Antigène: E2F5

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F5 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB23726

Détail du produit anti-E2F5 anticorps

Épitope: AA 66-93, N-Term

Homologie: M, X, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This E2F5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-93 amino acids from the N-terminal region of human E2F5.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-E2F5 (ABIN652951)

Song, Gong, Yan, Hong, Wang, Wu, Li, Li, Cao: "Sj7170, a unique dual-function peptide with a specific ?-chymotrypsin inhibitory activity and a potent tumor-activating effect from scorpion venom." dans: The Journal of biological chemistry, Vol. 289, Issue 17, pp. 11667-80, (2014) (PubMed).

Détails sur E2F5

Antigène: E2F5

Autre désignation: E2F5

Sujet: E2F5 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB.

Poids moléculaire: 37610

ID gène: 1875

NCBI Accession: NP_001077057, NP_001077058, NP_001942

UniProt: Q15329