GINS1 anticorps (N-Term)

N° du produit ABIN653447

L’anticorps Lapin Polyclonal anti-GINS1 a été validé pour WB. Il convient pour détecter GINS1 dans des échantillons de Humain. Il y a 2+ publications disponibles.

Aperçu rapide pour GINS1 anticorps (N-Term) (ABIN653447)

Antigène: GINS1 (GINS Complex Subunit 1 (Psf1 Homolog) (GINS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GINS1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB23977

Détail du produit anti-GINS1 anticorps

Épitope: AA 1-30, N-Term

Homologie: M

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This GINS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GINS1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-GINS1 (ABIN653447)

Kang, Farina, Bermudez, Tappin, Du, Galal, Hurwitz: "Interaction between human Ctf4 and the Cdc45/Mcm2-7/GINS (CMG) replicative helicase." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 49, pp. 19760-5, (2013) (PubMed).

Kang, Galal, Farina, Tappin, Hurwitz: "Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 16, pp. 6042-7, (2012) (PubMed).

Détails sur GINS1

Antigène: GINS1 (GINS Complex Subunit 1 (Psf1 Homolog) (GINS1))

Autre désignation: GINS1

Sujet: The yeast heterotetrameric GINS complex is made up of Sld5 (GINS4, MIM 610611), Psf1, Psf2 (GINS2, MIM 610609), and Psf3 (GINS3, MIM 610610). The formation of the GINS complex is essential for the initiation of DNA replication in yeast and Xenopus egg extracts (Ueno et al., 2005 [PubMed 16287864]).

Poids moléculaire: 22988

ID gène: 9837

NCBI Accession: NP_066545

UniProt: Q14691

Pathways: DNA Replication, Synthesis of DNA