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COX6A2 anticorps (AA 37-66)

Cet anticorps Lapin Polyclonal détecte spécifiquement COX6A2 dans WB et IHC (p). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.
N° du produit ABIN653569

Aperçu rapide pour COX6A2 anticorps (AA 37-66) (ABIN653569)

Antigène

Voir toutes COX6A2 Anticorps
COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

Reactivité

  • 19
  • 9
  • 1
  • 1
Humain

Hôte

  • 19
Lapin

Clonalité

  • 19
Polyclonal

Conjugué

  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp COX6A2 est non-conjugé

Application

  • 12
  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB23260
  • Épitope

    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 37-66

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This COX6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human COX6A2.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:1000. WB: 1:1000. IHC-P: 1:25

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Boczonadi, Giunta, Lane, Tulinius, Schara, Horvath: "Investigating the role of the physiological isoform switch of cytochrome c oxidase subunits in reversible mitochondrial disease." dans: The international journal of biochemistry & cell biology, (2015) (PubMed).

  • Antigène

    COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

    Autre désignation

    COX6A2

    Sujet

    Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.

    Poids moléculaire

    10815

    ID gène

    1339

    NCBI Accession

    NP_005196

    UniProt

    Q02221
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