COX6A2 anticorps (AA 37-66)
Aperçu rapide pour COX6A2 anticorps (AA 37-66) (ABIN653569)
Antigène
Voir toutes COX6A2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 37-66
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This COX6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the Central region of human COX6A2.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. WB: 1:1000. IHC-P: 1:25
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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: "Investigating the role of the physiological isoform switch of cytochrome c oxidase subunits in reversible mitochondrial disease." dans: The international journal of biochemistry & cell biology, (2015) (PubMed).
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- COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))
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Autre désignation
- COX6A2
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Sujet
- Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.
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Poids moléculaire
- 10815
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ID gène
- 1339
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NCBI Accession
- NP_005196
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UniProt
- Q02221
Antigène
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