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AANAT anticorps (N-Term)

Cet anticorps Lapin Polyclonal détecte spécifiquement AANAT dans WB. Il présente une réactivité envers Humain.
N° du produit ABIN653578

Aperçu rapide pour AANAT anticorps (N-Term) (ABIN653578)

Antigène

Voir toutes AANAT Anticorps
AANAT (Aralkylamine N-Acetyltransferase (AANAT))

Reactivité

  • 37
  • 18
  • 17
  • 1
Humain

Hôte

  • 39
  • 1
Lapin

Clonalité

  • 39
  • 1
Polyclonal

Conjugué

  • 13
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp AANAT est non-conjugé

Application

  • 16
  • 15
  • 14
  • 14
  • 5
  • 5
  • 4
  • 4
  • 4
  • 1
  • 1
Western Blotting (WB)

Clone

RB23834
  • Épitope

    • 15
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 27-54, N-Term

    Purification

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogène

    This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT.

    Isotype

    Ig Fraction
  • Indications d'application

    WB: 1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Date de péremption

    6 months
  • Antigène

    AANAT (Aralkylamine N-Acetyltransferase (AANAT))

    Autre désignation

    AANAT

    Sujet

    AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.

    Poids moléculaire

    23344

    ID gène

    15

    NCBI Accession

    NP_001079, NP_001160051

    UniProt

    Q16613

    Pathways

    Photoperiodism
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