AANAT anticorps (N-Term)
Aperçu rapide pour AANAT anticorps (N-Term) (ABIN653578)
Antigène
Voir toutes AANAT AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 27-54, N-Term
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This AANAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-54 amino acids from the N-terminal region of human AANAT.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- AANAT (Aralkylamine N-Acetyltransferase (AANAT))
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Autre désignation
- AANAT
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Sujet
- AANAT belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome.
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Poids moléculaire
- 23344
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ID gène
- 15
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NCBI Accession
- NP_001079, NP_001160051
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UniProt
- Q16613
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Pathways
- Photoperiodism
Antigène
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