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WASP anticorps (AA 116-144)

WAS Reactivité: Humain, Souris WB, IHC (p), FACS Hôte: Lapin Polyclonal RB23643 unconjugated
N° du produit ABIN653830
  • Antigène Voir toutes WASP (WAS) Anticorps
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Épitope
    • 15
    • 14
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 116-144
    Reactivité
    • 87
    • 54
    • 19
    • 2
    • 1
    • 1
    • 1
    Humain, Souris
    Hôte
    • 83
    • 4
    • 1
    Lapin
    Clonalité
    • 84
    • 4
    Polyclonal
    Conjugué
    • 34
    • 8
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp WASP est non-conjugé
    Application
    • 62
    • 37
    • 25
    • 15
    • 13
    • 13
    • 8
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogène
    This WAS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 116-144 amino acids from the Central region of human WAS.
    Clone
    RB23643
    Isotype
    Ig Fraction
    Top Product
    Discover our top product WAS Anticorps primaire
  • Indications d'application
    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Date de péremption
    6 months
  • Antigène
    WASP (WAS) (Wiskott-Aldrich Syndrome (Eczema-thrombocytopenia) (WAS))
    Autre désignation
    WAS (WAS Produits)
    Synonymes
    anticorps IMD2, anticorps SCNX, anticorps THC, anticorps THC1, anticorps WASP, anticorps U42471, anticorps WASp, anticorps Wasp, anticorps imd2, anticorps thc, anticorps thc1, anticorps was, anticorps wasp, anticorps wu:fk81c08, anticorps zgc:64164, anticorps Wiskott-Aldrich syndrome, anticorps neural Wiskott-Aldrich syndrome protein, anticorps wiskott-aldrich syndrome protein, anticorps Wiskott-Aldrich syndrome L homeolog, anticorps Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b, anticorps WAS, anticorps LOC5578888, anticorps CpipJ_CPIJ006699, anticorps Was, anticorps was.L, anticorps wasb
    Sujet
    The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients.
    Poids moléculaire
    52913
    ID gène
    7454
    NCBI Accession
    NP_000368
    UniProt
    P42768
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