AMH anticorps (AA 424-451)

N° du produit ABIN653897

L’anticorps Lapin Polyclonal anti-AMH a été validé pour WB, FACS et IHC (p). Il convient pour détecter AMH dans des échantillons de Humain et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour AMH anticorps (AA 424-451) (ABIN653897)

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AMH est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-AMH anticorps

Épitope: AA 424-451

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This AMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 424-451 amino acids of human AMH.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000-1:2000. IHC-P: 1:25. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-AMH (ABIN653897)

Jin, Won, Park, Lee, Park, Bae: "FOXL2 Is an Essential Activator of SF-1-Induced Transcriptional Regulation of Anti-Müllerian Hormone in Human Granulosa Cells." dans: PLoS ONE, Vol. 11, Issue 7, pp. e0159112, (2017) (PubMed).

Park, Suh, Lee, Bae: "Positive cross talk between FOXL2 and antimüllerian hormone regulates ovarian reserve." dans: Fertility and sterility, (2014) (PubMed).

Détails sur AMH

Antigène: AMH (Anti-Mullerian Hormone (AMH))

Autre désignation: AMH

Sujet: Anti mullerian hormone (AMH) is a member of the TGF beta superfamily. It is secreted as a homodimeric 140kD disulphide linked precursor that is cleaved to release the mature 30kD homodimer. Originally classified as a foetal testicular hormone that inhibits Mullerian duct development, AMH is expressed post natally by immature Sertoli cells, and to a lesser degree by granulosa cells. AMH plays a role in testicular differentiation and in the regulation of ovarian follicle growth.

Poids moléculaire: 59195

ID gène: 268

NCBI Accession: NP_000470

UniProt: P03971

Pathways: Negative Regulation of Hormone Secretion