MUC1 anticorps (AA 1202-1231)

N° du produit ABIN654056

L’anticorps Lapin Polyclonal anti-MUC1 a été validé pour WB. Il convient pour détecter MUC1 dans des échantillons de Humain.

Aperçu rapide pour MUC1 anticorps (AA 1202-1231) (ABIN654056)

Antigène: MUC1 (Mucin 1 (MUC1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC1 est non-conjugé

Application: Western Blotting (WB)

Clone: RB16593

Détail du produit anti-MUC1 anticorps

Épitope: AA 1202-1231

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This MUC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1202-1231 amino acids from human MUC1.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur MUC1

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1

Sujet: This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq].

Poids moléculaire: 122102

ID gène: 4582

NCBI Accession: NP_001018016, NP_001018017, NP_001037855, NP_001037856, NP_001037857, NP_001037858, NP_001191214, NP_001191215, NP_001191216, NP_001191217, NP_001191218, NP_001191219, NP_001191220, NP_00

UniProt: P15941

Pathways: Negative Regulation of intrinsic apoptotic Signaling