ALOXE3 anticorps (AA 223-252)

N° du produit ABIN654408

Cet anticorps anti-ALOXE3 Polyclonal Lapin (Clone RB17172) (ABIN654408) détecte spécifiquement ALOXE3 dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ALOXE3 anticorps (AA 223-252) (ABIN654408)

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOXE3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB17172

Détail du produit anti-ALOXE3 anticorps

Épitope: AA 223-252

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This ALOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human ALOXE3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. IHC-P-Leica: 1:500. IHC-P-Leica: 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur ALOXE3

Antigène: ALOXE3 (Arachidonate Lipoxygenase 3 (ALOXE3))

Autre désignation: ALOXE3

Sujet: ALOXE3 is a member of the lipoxygenase family, which are catabolized by arachidonic acid-derived compounds. The encoded enzyme is a hydroperoxide isomerase that synthesizes a unique type of epoxy alcohol (8R-hydroxy-11R,12R-epoxyeicosa-5Z,9E,14Z-trienoic acid) from 12R-hydroperoxyeicosatetraenoic acid (12R-HPETE). This epoxy alcohol can activate the the nuclear receptor peroxisome proliferator-activated receptor alpha (PPARalpha), which is implicated in epidermal differentiation. Loss of function of the enzyme encoded by this gene results in ichthyosis, implicating the function of this gene in the differentiation of human skin.

Poids moléculaire: 80543

ID gène: 59344

NCBI Accession: NP_001159432, NP_067641

UniProt: Q9BYJ1

Pathways: Cell-Cell Junction Organization