CCR8 anticorps (AA 305-335)
Aperçu rapide pour CCR8 anticorps (AA 305-335) (ABIN654442)
Antigène
Voir toutes CCR8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 305-335
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids of human CCR8.
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Isotype
- IgG
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Indications d'application
- WB: 1:1000. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))
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Autre désignation
- CCR8
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Sujet
- CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
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Poids moléculaire
- 40844
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ID gène
- 1237
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NCBI Accession
- NP_005192
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UniProt
- P51685
Antigène
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