CCR8 anticorps (AA 305-335)

N° du produit ABIN654442

Détail du produit anti-CCR8 anticorps

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Épitope: AA 305-335

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR8 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CCR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-335 amino acids of human CCR8.

Clone: RB28557

Isotype: IgG

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur CCR8

Antigène: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Autre désignation: CCR8 (CCR8 Produits)

Synonymes: anticorps CC-CKR-8, anticorps CCR-8, anticorps CDw198, anticorps CKRL1, anticorps CMKBR8, anticorps CMKBRL2, anticorps CY6, anticorps GPRCY6, anticorps TER1, anticorps C-C, anticorps C-C CKR-8, anticorps CKR-8, anticorps Cmkbr8, anticorps mCCR8, anticorps C-C motif chemokine receptor 8, anticorps chemokine (C-C motif) receptor 8, anticorps CCR8, anticorps Ccr8

Sujet: CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.

Poids moléculaire: 40844

ID gène: 1237

NCBI Accession: NP_005192

UniProt: P51685