This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-180 amino acids from the N-terminal region of human C2.
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogène
This C2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 AA from the N-terminal region of human C2.
Reactivité: Humain, Rat, Souris, Cheval, Porc, Boeuf (Vache), Singe
WB
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
WB = 1:1000
Restrictions
For Research Use only
Format
Liquid
Concentration
0.26 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C/-20 °C
Stockage commentaire
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Date de péremption
6 months
Antigène
Complement C2
Autre désignation
C2
Sujet
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined. Synonyms: Complement C2,C2,