IL12_2 (AA 756-783), (C-Term) anticorps

N° du produit ABIN654644

L’anticorps Lapin Polyclonal anti- a été validé pour FACS, WB et IHC (p). Il convient pour détecter dans des échantillons de Humain.

Aperçu rapide pour IL12_2 (AA 756-783), (C-Term) anticorps (ABIN654644)

Antigène: IL12_2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB28530

Détail du produit

Épitope: AA 756-783, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This IL12_2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 756-783 amino acids from the C-terminal region of human IL12_2.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détail du antigène

Antigène: IL12_2

Sujet: The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.

Poids moléculaire: 97135

ID gène: 3595

NCBI Accession: NP_001245143, NP_001245144, NP_001245145, NP_001550

UniProt: Q99665