ARHGAP10 anticorps (AA 237-263)
Aperçu rapide pour ARHGAP10 anticorps (AA 237-263) (ABIN654652)
Antigène
Voir toutes ARHGAP10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 237-263
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Homologie
- B
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Purification
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogène
- This ARHGAP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 237-263 amino acids from the Central region of human ARHGAP10.
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Isotype
- Ig Fraction
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Indications d'application
- WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Date de péremption
- 6 months
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- ARHGAP10 (rho GTPase Activating Protein 10 (ARHGAP10))
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Autre désignation
- ARHGAP10
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Sujet
- GTPase activator for the small GTPases RhoA and Cdc42 by converting them to an inactive GDP-bound state. Essential for PTKB2 regulation of cytoskeletal organization via Rho family GTPases. Inhibits PAK2 proteolytic fragment PAK-2p34 kinase activity and changes its localization from the nucleus to the perinuclear region. Stabilizes PAK-2p34 thereby increasing stimulation of cell death (By similarity).
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Poids moléculaire
- 89375
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ID gène
- 79658
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NCBI Accession
- NP_078881
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UniProt
- A1A4S6
Antigène
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