Endothelin 3 anticorps (C-Term)

N° du produit ABIN655169

L’anticorps anti-Endothelin 3 Polyclonal Lapin est utilisé pour la détection de Endothelin 3 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Endothelin 3 anticorps (C-Term) (ABIN655169)

Antigène: Endothelin 3 (EDN3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Endothelin 3 est non-conjugé

Application: Western Blotting (WB)

Clone: RB18967

Détail du produit anti-Endothelin 3 anticorps

Épitope: AA 168-197, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This EDN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the C-terminal region of human EDN3.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Détails sur Endothelin 3

Antigène: Endothelin 3 (EDN3)

Autre désignation: EDN3

Sujet: The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.

Poids moléculaire: 25454

ID gène: 1908

NCBI Accession: NP_000105, NP_996915, NP_996916, NP_996917

UniProt: P14138

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones