HOPX anticorps (C-Term)

N° du produit ABIN655402

Cet anticorps Lapin Polyclonal détecte spécifiquement HOPX dans WB et FACS. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour HOPX anticorps (C-Term) (ABIN655402)

Antigène: HOPX (HOP Homeobox (HOPX))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HOPX est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: RB18900

Détail du produit anti-HOPX anticorps

Épitope: AA 39-67, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This HOPX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-67 amino acids from the C-terminal region of human HOPX.

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Date de péremption: 6 months

Références pour anticorps anti-HOPX (ABIN655402)

Kovárová, Plachy, Kosla, Trejbalová, ?ermák, Hejnar: "Downregulation of HOPX controls metastatic behavior in sarcoma cells and identifies genes associated with metastasis." dans: Molecular cancer research : MCR, Vol. 11, Issue 10, pp. 1235-47, (2013) (PubMed).

Détails sur HOPX

Antigène: HOPX (HOP Homeobox (HOPX))

Autre désignation: HOPX

Sujet: The protein encoded by this gene is a homeodomain protein that lacks certain conserved residues required for DNA binding. It was reported that choriocarcinoma cell lines and tissues failed to express this gene, which suggested the possible involvement of this gene in malignant conversion of placental trophoblasts. Studies in mice suggest that this protein may interact with serum response factor (SRF) and modulate SRF-dependent cardiac-specific gene expression and cardiac development. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq].

ID gène: 84525

NCBI Accession: NP_001138931, NP_001138932, NP_115884, NP_631957, NP_631958

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation